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Patients taking testosterone and proprantolol together for decreased therapeutic efficacy of propranolol. Testosterone has been tested by subcutaneous injection and implantation in mice and rats. Elevated levels of vasopressin increased expression of AQP1 in trophoblast cells Belkacemi et al (2008). This strategy is sometimes used when a drug has pharmacokinetic or solubility problems when used. The different testosterone esters provide for different elimination half-lives in the body. Produced by the adrenal glands in both males and females and, in small amounts, by the ovaries in females.
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